Study Materials

The list below contains optional readings and videos for each unit of the course.

Biochemistry

Genetics

Molecular Biology

Recombinant DNA Module

Cell Biology

Applied Modules and Diseases

Biochemistry

Genetic Science Learning Center. "Cell Size and Scale," Learn.Genetics. June 22, 2014.

Wenz, J. "The Other Neanderthal," The Atlantic, August 27, 2014.

Mr. Kent's Chemistry Page. "Bonds in Biological Molecules."

Halpine, Susanna. "Membrane Structure: The Fluid Mosaic Model." Developed for "Life, 6th ed." © Sinauer Associates, Inc., W. H. Freeman Co. and Sumanas Inc. 2000. Accessed September 16, 2014.

Kyrk, John. "Cell Membranes Animation." November 12, 2013.

Liu, Q. P., G. Sulzenbacher, et al. "Bacterial Glycosidases for The Production of Universal Red Blood Cells." Nature Biotechnology 25 (2007): 454–64.

"How Geckos Stick—New Find May Lead to New Glue." National Geographic News, August 28, 2002.

RedAndr. "GCSF Protein Folding Illustration Movie." May 8, 2007. YouTube. Accessed September 16, 2014. http://www.youtube.com/watch?v=swEc_sUVz5I

Sawaya, M. R., and J. Kraut. "Loop and Domain Movements in the Mechanism of E. Coli Dihydrofolate Reductase: Crystallographic Evidence." Biochemistry 36 (1997): 586–603. DHFR the Movie.

Amazon logo Seeley, Rod R. "Animation: Feedback Inhibition of Biochemical Pathways." In Essentials of Anatomy and Physiology. McGraw-Hill Higher Education, 2000. ISBN: 9780072943696.

Watson, J. D., and F. H. C. Crick. This resource may not render correctly in a screen reader."Molecular Structure of Nucleic Acids." (PDF) Nature 171 (1953): 737–8.

Genetics

Nova beta, "How Cells Divide," PBS Online by WGBH.

Miko, I. "Thomas Hunt Morgan and Sex Linkage." Scitable by Nature Education 1, no. 1 (2008).

Sturtevant, A. H. This resource may not render correctly in a screen reader. "The Linear Arrangement of Six Sex-Linked Factors in Drosophila, as Shown by Their Mode of Association." Journal of Experimental Zoology 14 (1913): 43–59. (PDF)

"Possible Role for Huntington's Gene Discovered." MIT News Office, January 16, 2013.

Weiss, R. "U.S. Neurologist Wins Nobel Prize for Discovery of Prions." The Tech Online Edition 117, no. 48 (1997).

Molecular Biology

Berry, Drew. "Molecular Visualizations of DNA," The Walter and Eliza Hall Institute of Medical Research. 2003. Accessed February 25, 2015. http://www.wehi.edu.au/wehi-tv/molecular-visualisations-dna

Bozeman Science. "A Tour of the Cell." February 24, 2012. YouTube. Accessed September 16, 2014. http://www.youtube.com/watch?v=1Z9pqST72is

"Animation: Meselson and Stahl Experiment." McGraw-Hill Higher Education.

Matthew Cook. "DNA Replication." February 12, 2008. YouTube. Accessed February 27, 2015. https://www.youtube.com/watch?v=4jtmOZaIvS0

Clancy, S. "DNA Damage & Repair: Mechanisms for Maintaining DNA Integrity: Mechanisms for Maintaining DNA Integrity." Nature Education 1, no.1 (2008): 103.

Rufus Rajadurai. "RNA Animation." May 10, 2007. YouTube. Accessed February 27, 2015. https://www.youtube.com/watch?v=Ml0OqAUzEXU&list=PL1AD35ADA1E93EB6F

Hardesty, L. "Deciphering the Language of Transcription Factors," MIT News, September 10, 2012.

Cold Spring Harbor Laboratory. "3D Animation of RNA Splicing." DNA Learning Center, Cold Spring Harbor Laboratory.

"Animation: How Spliceosomes Process RNA." McGraw-Hill Higher Education.

Trafton, A. "Evolution: It's all about How you Splice it," MIT News, December 20, 2012.

"Animation: Processing of Gene Information: Prokaryotes vs. Eukaryotes." McGraw-Hill Higher Education.

Amazon logo Macario, A. J. L., Everly Conway de Macario, and Francesco Capello. "Chaperones: General Characteristics and Classifications." Chapter 2 in The Chaperonopathies Diseases with Defective Molecular Chaperones. Springer, 2013. ISBN: 9789400746664. [Preview with Google Books]

Recombinant DNA Module

Deerforum. "Plasmid Cloning." August 14, 2007. YouTube. Accessed February 27, 2015. http://www.youtube.com/watch?v=acKWdNj936o&feature=related

Mullis, Kary B., and Michael Smith. "The 1993 Nobel Prize in Chemistry." Nobelprize.org. The Nobel Foundation, 1993.

Cold Spring Harbor Laboratory. "3D Animation: The Cycles of the Polymerase Chain Reaction (PCR)." DNA Learning Center, Cold Spring Harbor Laboratory.

Bio-Rad. "Scientists for Better PCR." Bio-Rad. Accessed February 27, 215. http://www.cnpg.com/video/flatfiles/539/

Draven1983101. "Illumina Solexa Sequencing." January 22, 2010. YouTube. Accessed February 27, 2015. https://www.youtube.com/watch?v=77r5p8IBwJk

Illumina Inc. "Illumina Sequencing Technology." October 23, 2013. YouTube. Accessed February 27, 2015. https://www.youtube.com/watch?v=womKfikWlxM

23andMe. https://www.23andme.com/

Rojahn, Susan Young. "Gene Therapy Tested as a Way to Stop Blindness." The MIT Technology Review, January 16, 2014.

Biotechnology Industry Organization. "New Hope for Gene Therapy...A Young Boy's Fight Against Blindness." May 5, 2010. YouTube. Accessed February 27, 2015. https://www.youtube.com/watch?v=H0RvTOF1fEc

Cell Biology

Shimomura, Osamu, Martin Chalfie, et al. "The 2008 Nobel Prize in Chemistry." Nobelprize.org, October 8, 2008.

iBioMagazine. "Martin Chalfie (Columbia University): Developing GFP as a Biological Marker." June 18, 2011. YouTube. Accessed September 17, 2014. http://www.youtube.com/watch?v=cfg75ft7oOw

Chandler, David L. "Living Cells Say: Can You Hear Me Now?" MIT News Office, November 17, 2011.

Scottish Enterprise. "Ubiquitin Proteasome System programme." February 23, 2011. YouTube. Accessed February 27, 2015. https://www.youtube.com/watch?v=hvNJ3yWZQbE

Saville, Diana. "SRP, 3D Animatic." July 20, 2010. YouTube. Accessed September 17, 2014. http://www.youtube.com/watch?v=ScAu0MZK3CU&feature=related

Bensaccount. Protein translation.gif. Wikimedia Commons, July 2009.

Genetic Science Learning Center. "DNA Microarray," Learn.Genetics. June 22, 2014.

Applied Modules and Diseases

Weiss, R. A., and P. K. Vogt. "100 Years of Rous Sarcoma Virus." Journal of Experimental Medicine 208, no.12 (2011): 2351–55.

Hanahan, D., and R. A. Weinberg. "The Hallmarks of Cancer." Cell 100 (2000): 57–70.

Tonegawa, Susumu. "The Nobel Prize in Physiology or Medicine 1987." Nobelprize.org. The Nobel Foundation, 1987.

Autoimmune Disease Research Center. Johns Hopkins Medical Institutions. Johns Hopkins University School of Medicine & Johns Hopkins Health System.

Classification of Viruses. Virology Tutorials, Beuret Christian.

"Animation of HIV life cycle." DNAtube, scientific video site. Accessed February 27, 2015. http://www.dnatube.com/video/12229/Animation-of-HIV-life-cycle

"Finding a Cure: Is an AIDS Vaccine Out of Reach?" Frontline, WGBH, May 30, 2006.

Smith-Spark, L. "Scientists: 'Positive' Results in 1st Human Trial of Experimental Ebola Vaccine." CNN News, November 29, 2014.