Before each class, students will formulate 2–3 questions to facilitate discussions. These questions are due by 10 pm on the day before class and should be related to the assigned papers for that week. Questions may be about the papers' background material, techniques, data generation and analysis, interpretation of results or follow-up experiments.
Write a short summary and critique of the distributed paper:
Stoeckius, M., D. Grun, and N. Rajewsky. "Paternal RNA contributions in the Caenorhabditis elegans zygote." EMBO Journal 33(2014): 1740–50.
Include the following components:
You are encouraged to consult Pubmed, the Internet, textbooks, friends, and each other for ideas and examples of possible follow-up experiments.
In Week 9, we will use our class to do a mock peer review of the student proposals. Each student will be assigned a classmate's proposal and will lead a brief discussion of its strengths and weaknesses for the class. The goal of this exercise is to introduce students to the process of peer review first-hand. The focus will be on improving rather than simply criticizing the proposal.
On the last day of class, students will give a 15 minute presentation about a paper related to one of the topics discussed in this course. The students should choose a paper themselves and then discuss it with the instructors to be sure an appropriate paper has been selected. The deadline for choosing a paper is Week 11. The presentation should be about 10 slides long and prepared using PowerPoint or other slide presentation software. At the end of each presentation, we will have 5 minutes for questions and discussion. The presentation should have the following format: